Intratype variation in 12 human papillomavirus types: More From Thought Catalog. These independent studies are from three areas of grand China, Mainland China, Taiwan, and Hong Kong, suggesting that host genetic makeup may play an important role in susceptibility to HPV infection. Among the nonmalignant tissues, 24 were ovaries removed for uterine pathology, five were ovarian cysts, and one was polycystic ovarian syndrome. Human papillomavirus type 16 sequence variation in cervical cancers: However, there are reports suggesting that the association between HPV infection and p53 mutation differs among tumours Hachisuga et al; Hasegawa et al, suggesting that additional mechanisms may be involved in tumorigenesis of other origins. The expression of p53 was not correlated with HPV infection.
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The hybridisation solution without probes has been used as negative control.
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Therefore, p53 mutation is rare in cervical cancers. These results indicate that IHC is an accurate method with less sensitivity. Specimens were paraffin-embedded and archived from — in Inner Mongolia Medical College affiliated hospital. The paraffin sections were dewaxed, rehydrated and treated with 0. Clonal p53 mutation in primary cervical cancer: